tag:blogger.com,1999:blog-256015672011-04-22T00:42:26.231+01:00Teresa Cunha Oliveirahttp://www.blogger.com/profile/15891386575611824823noreply@blogger.comBlogger41100tag:blogger.com,1999:blog-25601567.post-6034016183227297112008-05-27T11:19:00.004+01:002008-05-27T11:25:20.806+01:00This is the group's new website:<br /><br /><a href="http://sites.google.com/site/mitochondrialdysfunction/">http://sites.google.com/site/mitochondrialdysfunction/</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/25601567-603401618322729711?l=mitochondrialdysfunction.blogspot.com' alt='' /></div>Teresa Cunha Oliveirahttp://www.blogger.com/profile/15891386575611824823noreply@blogger.com0tag:blogger.com,1999:blog-25601567.post-1144422119279760512006-04-07T15:59:00.000+01:002006-04-10T21:52:59.106+01:00<p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://photos1.blogger.com/blogger/7093/2394/1600/mitogroup%20logo2.jpg"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer;" src="http://photos1.blogger.com/blogger/7093/2394/400/mitogroup%20logo2.jpg" alt="" border="0" /></a><span lang="EN-GB" style="font-family:Arial;">The main purpose of our <a href="http://www.uc.pt/cnc/GroupsEng/mitochondrial.php">group</a> is the study of basic mechanisms underlying selective </span><span lang="EN-GB" style="font-family:Arial;">neurodegeneration involving mitochondrial dysfunction in neurodegenerative disorders. By accomplishing this, we hope to bring about new therapeutic strategies to neurodegenerative diseases.<u1:p></u1:p><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;">The structure of group can be defined in terms of research interests. Here you can find a list of our ongoing research projects and its participants and funding.</span></p><span style=";font-family:&quot;;font-size:12;" ><a href="http://www.uc.pt/cnc/GroupsEng/mitochondrial.php"></a></span><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/25601567-114442211927976051?l=mitochondrialdysfunction.blogspot.com' alt='' /></div>Teresa Cunha Oliveirahttp://www.blogger.com/profile/15891386575611824823noreply@blogger.com0tag:blogger.com,1999:blog-25601567.post-1144420449479021502006-04-07T15:27:00.002+01:002008-04-16T14:00:16.038+01:00<h3 style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span style="color: rgb(204, 0, 0);font-family:Arial;" lang="EN-GB"><u1:p></u1:p></span><span style="font-size:130%;"><strong style="color: rgb(0, 0, 153);"><span style="font-variant: small-caps;font-family:Arial;" lang="EN-GB">1.1 Polyglutamine expansion diseases</span></strong></span><span lang="EN-GB" style="font-family:Arial;"> <o:p></o:p></span></h3> <u1:p></u1:p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span style="font-family:Arial;"><span style="color: rgb(51, 102, 255);">Research team</span>: <a href="http://acrego.blogspot.com/">A. Cristina Rego</a> (PhD), <a href="http://catarinaroliveira.blogspot.com/">Catarina R. Oliveira</a> (MD, PhD), Mário Laço (UC PhD stud.), <a href="http://sandra-almeida.blogspot.com/">Sandra Almeida</a> (UC PhD)<u1:p></u1:p><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;"><span style="color: rgb(51, 102, 255);">Collaborators</span>: David G. Nicholls and Lisa Ellerby (<a href="http://www.buckinstitute.org/faculty.aspx?id=877">Buck Institute, Novato, CA, USA</a>); Henry Paulson (<a href="http://molbio.grad.uiowa.edu/Faculty/FacultyDetail.asp?name=Henry+Paulson">Iowa University, Iowa, USA</a>); Jorge Gonçalves (<a href="http://sigarra.up.pt/ffup/unidades_geral.visualizar?p_unidade=81">Fac. </a></span><span style="font-family:Arial;"><a href="http://sigarra.up.pt/ffup/unidades_geral.visualizar?p_unidade=81">Pharm, Univ. Porto, PT</a>); Patrícia Maciel (Minho University, PT) and Ana Luísa Carvalho (CNCB/UC).<u1:p></u1:p><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;"><span style="color: rgb(0, 0, 153);">1.1.1 </span>FK-506 and BDNF neuroprotection in a mitochondrial model of Huntington’s disease – <a href="http://sandra-almeida.blogspot.com/">Sandra Almeida</a><u1:p></u1:p><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;"><span style="color: rgb(0, 0, 153);">1.1.2</span> Mitochondrial dysfunction and nuclear aggregation of expanded ataxin-<st1:metricconverter productid="3 in" st="on"><st1:metricconverter productid="3 in" st="on">3 in</st1:metricconverter></st1:metricconverter> cell models of Machado-Joseph disease – Mário Laço<u1:p></u1:p><o:p></o:p></span></p> <h3 style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><strong><span lang="EN-GB" style="font-family:Arial;"><u1:p></u1:p><span style="color: rgb(0, 0, 153); font-weight: normal;font-size:130%;" >2. CELL DEGENERATION AND PROTECTION</span></span></strong><span lang="EN-GB" style="font-family:Arial;"><u1:p></u1:p><o:p></o:p></span></h3> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><strong><span style="font-variant: small-caps;font-family:Arial;" lang="EN-GB"><span style="color: rgb(0, 0, 153); font-weight: bold;">2.1 oxidative stress</span><u1:p></u1:p></span></strong><span lang="EN-GB" style="font-family:Arial;"><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span style="font-family:Arial;"><span style="color: rgb(51, 102, 255);">Research Team:</span> <a href="http://acrego.blogspot.com/">A. Cristina Rego</a> (PhD), <a href="http://anaduarte.blogspot.com/">Ana Duarte</a> (PhD), <a href="http://catarinaroliveira.blogspot.com/">Catarina R. Oliveira</a> (MD, PhD), <a href="http://ritaperfeito.blogspot.com/">Rita Perfeito</a> (PhD student), Sancha M. Santos (PhD)<u1:p></u1:p><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;"><span style="color: rgb(51, 102, 255);">Collaborators:</span> João Bettencourt-Relvas and Jorge Pereira (<a href="http://www.cell.biol.ethz.ch/research/relvas/">Federal Institute of Technology <st1:place st="on"><st1:city st="on"><st1:place st="on"><st1:city st="on">Zurich</st1:city></st1:place>, <st1:country-region st="on"><st1:country-region st="on">Switzerland</st1:country-region></st1:country-region></st1:city></st1:place></a>)<u1:p></u1:p><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;"><span style="color: rgb(0, 0, 153);">2.1.1</span> Insulin neuroprotection against neuronal oxidative stress – <a href="http://anaduarte.blogspot.com/">Ana <st1:place st="on"><st1:city st="on">Duarte</st1:city></st1:place></a><u1:p></u1:p><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;"><span style="color: rgb(0, 0, 153);">2.1.2 </span>Oxidative lesion of oligodendrocytes and role of antioxidants – <a href="http://ritaperfeito.blogspot.com/">Rita Perfeito</a><u1:p></u1:p><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><strong><span style="font-variant: small-caps;font-family:Arial;" lang="EN-GB"><span style="color: rgb(51, 153, 153);font-size:100%;" ><span style="color: rgb(0, 0, 153);">2.2 Neurotoxicity of drugs of abuse</span></span><u1:p></u1:p></span></strong><span lang="EN-GB" style="font-family:Arial;"><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;"><span style="color: rgb(0, 0, 153);font-size:100%;" >Research Team</span>: <a href="http://acrego.blogspot.com/">A. Cristina Rego</a> (PhD), <a href="http://catarinaroliveira.blogspot.com/">Catarina R. Oliveira</a> (MD, PhD), <a href="http://teresacunhaoliveira.blogspot.com/">Teresa Cunha Oliveira</a> (PhD)<u1:p></u1:p><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;">Collaborators: Tice Macedo (FMED, UC), <a href="http://www.uc.pt/qfm/fernanda_borges.html">Fernanda Borges</a> (Fac. Pharm, Univ. </span><st1:place st="on"><st1:place st="on"><span style="font-family:Arial;">Porto</span></st1:place></st1:place><span style="font-family:Arial;">, PT), <a href="http://www.uc.pt/qfm/paula_marques.html">Paula Marques</a> (FCTUC, PT), <a href="http://www.ectep.com/teses/teses/ficha.asp?PnIDFac=4&amp;PnIDEspec=15&amp;PID=631">Ana Paula Silva</a> (FMED, UC).<u1:p></u1:p><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><b><span style="font-family:Arial;"><span style="font-size:130%;"><span style="color: rgb(0, 0, 153);">3. NEURAL STEM CELL RESEARCH</span></span><u1:p></u1:p></span></b><span style="font-family:Arial;"><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span style="font-family:Arial;"><span style="color: rgb(51, 102, 255);">Research Team</span>: <a href="http://acrego.blogspot.com/">A. Cristina Rego</a> (PhD), <a href="http://anacrsilva.blogspot.com/">Ana C. Silva</a> (UC PhD stud.), <a href="http://catarinaroliveira.blogspot.com/">Catarina R. Oliveira</a> (MD, PhD),<u1:p></u1:p><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span style="font-family:Arial;"><span style="color: rgb(51, 102, 255);">Collaborators</span>: João Bettencourt-Relvas and Jorge Pereira (<a href="http://www.cell.biol.ethz.ch/research/relvas/">Federal Institute of Technology Zurich, Switzerland</a>), <a href="http://www.ectep.com/teses/teses/ficha.asp?PnIDFac=5&amp;PnIDEspec=169&amp;PID=722">Luís Pe<span style="font-size:100%;">r</span>eira de Almeida</a> (CNCB/UC).</span></p><p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><br /><span style="font-family:Arial;"><u1:p></u1:p><o:p></o:p></span></p> <p style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><b><span style=";font-family:Arial;color:green;" ><u1:p></u1:p></span></b><span style=";font-family:Arial;color:green;" ><span style="font-size:180%;"><span style="color: rgb(0, 0, 153);">Future perspectives:</span></span></span><b><span style=";font-family:Arial;color:green;" > <u1:p></u1:p></span></b><span style="font-family:Arial;"><o:p></o:p></span></p> <p class="MsoNormal" style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;">Study of neurodegeneration involving mitochondrial dysfunction and on neural stem cells therapy, using cell and animal models of neurodegenerative diseases.</span></p><p class="MsoNormal" style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;"><br /></span></p><p class="MsoNormal" style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span style="font-family:Arial;"><span style="color: rgb(51, 102, 255);"><span style="font-size:130%;"><span style="color: rgb(0, 0, 153);">Group Members</span></span>:</span><u1:p></u1:p><o:p></o:p></span></p> <p class="MsoNormal" style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span style="font-family:Arial;"><a href="http://catarinaroliveira.blogspot.com/">Catarina Resende de Oliveira</a> (<span style="font-style: italic;">Director of CNCB</span>)<u1:p></u1:p><o:p></o:p></span></p> <p class="MsoNormal" style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;"><a href="http://acrego.blogspot.com/">Ana Cristina Carvalho Rego </a>(<span style="font-style: italic;">Head of the group</span>)<u1:p></u1:p></span></p><p class="MsoNormal" style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;"><u1:p> <!--[endif]--><o:p></o:p></u1:p> <span style="font-style: italic;font-size:100%;" >Post-Docs</span></span></p><p class="MsoNormal" style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;"><a href="http://anaduarte.blogspot.com/">Ana Duarte</a>, <a href="http://teresacunhaoliveira.blogspot.com/">Teresa Oliveira,</a><span style="font-style: italic;font-size:100%;" > </span></span><span style="font-family:Arial;"><a href="http://sandra-almeida.blogspot.com/">Sandra Almeida</a>, </span><span lang="EN-GB" style="font-family:Arial;"><span style="font-style: italic;font-size:100%;" >I. Luísa Ferreira<br /></span></span></p><p class="MsoNormal" style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span lang="EN-GB" style="font-family:Arial;"><span style="font-style: italic;font-size:100%;" >PhD students:</span><u1:p></u1:p><o:p></o:p></span></p> <p class="MsoNormal" style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span style="font-family:Arial;">Mário Laço, <a href="http://ritaperfeito.blogspot.com/">Rita Perfeito</a>, </span><span style="font-family:Arial;"><a href="http://anacrsilva.blogspot.com/">Ana Cristina Silva</a>, A. Catarina Oliveira, Susana Louros<br /></span></p><p class="MsoNormal" style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span style="font-family:Arial;"><u1:p></u1:p><span style="font-style: italic;">Master students</span>:<u1:p></u1:p><o:p></o:p></span></p> <p class="MsoNormal" style="text-align: justify; text-indent: 14.2pt; line-height: 150%;"><span style="font-family:Arial;">Maria Nascimento, Márcio Ribeiro</span></p><p class="MsoNormal" style="text-align: justify; text-indent: 14.2pt; line-height: 150%; font-style: italic;">Undergraduate students:</p><p class="MsoNormal" style="text-align: justify; text-indent: 14.2pt; line-height: 150%;">Rui Costa<br /><span style="font-family:Arial;"><o:p></o:p></span></p> <u1:p></u1:p><u1:p></u1:p><u1:p></u1:p><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/25601567-114442044947902150?l=mitochondrialdysfunction.blogspot.com' alt='' /></div>Teresa Cunha Oliveirahttp://www.blogger.com/profile/15891386575611824823noreply@blogger.com0tag:blogger.com,1999:blog-25601567.post-1144419965197373392006-04-07T15:24:00.001+01:002008-04-16T13:58:39.320+01:00<a href="http://acrego.blogspot.com/"><br /></a><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://photos1.blogger.com/blogger/7093/2394/1600/cristina.jpg"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 72px; height: 73px;" src="http://photos1.blogger.com/blogger/7093/2394/400/cristina.jpg" alt="" border="0" /></a><br /><a href="http://acrego.blogspot.com/">Ana Cristina Rego (PhD)</a> - Group leader<br /><br /><br /><br /> A. Catarina Oliveira (PhD student)<br /><br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://photos1.blogger.com/blogger/3023/2546/1600/anac2.jpg"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 44px; height: 81px;" src="http://photos1.blogger.com/blogger/3023/2546/1600/anac2.jpg" alt="" border="0" /></a><br /><br /><a href="http://anacrsilva.blogspot.com/">A</a><a href="http://anacrsilva.blogspot.com/">na Cristina Silva </a>(PhD student)<br /><br /><br /><br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://photos1.blogger.com/blogger/5584/2507/1600/ana.jpg"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 56px; height: 78px;" src="http://photos1.blogger.com/blogger/5584/2507/1600/ana.jpg" alt="" border="0" /></a><br /><a href="http://anaduarte.blogspot.com/">Ana Isabel Duarte</a> (MSc, PhD)<br /><br /><br /><br /><br />I. Luísa Ferreira (PhD)<br /><br /><br />Maria Nascimento (MSc student)<br /><br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://photos1.blogger.com/blogger/7093/2394/1600/marcio.jpg"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 67px; height: 76px;" src="http://photos1.blogger.com/blogger/7093/2394/320/marcio.jpg" alt="" border="0" /></a><br /><br />Márcio Ribeiro (MSc student)<br /><br /><br /><br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://photos1.blogger.com/blogger/7093/2394/1600/mario.jpg"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 75px; height: 85px;" src="http://photos1.blogger.com/blogger/7093/2394/400/mario.jpg" alt="" border="0" /></a><br /><br />Mário Laço (PhD student)<br /><br /><br /><br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://photos1.blogger.com/blogger/7093/2394/1600/sandra.jpg"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 78px; height: 76px;" src="http://photos1.blogger.com/blogger/7093/2394/400/sandra.jpg" alt="" border="0" /></a><br /><br /><a href="http://sandra-almeida.blogspot.com/">Sandra Almeida</a> (PhD)<br /><br /><br /><br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://photos1.blogger.com/blogger/7093/2394/1600/rita.jpg"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 78px; height: 88px;" src="http://photos1.blogger.com/blogger/7093/2394/400/rita.jpg" alt="" border="0" /></a><br /><br /><a href="http://ritaperfeito.blogspot.com/">Rita Perfeito</a> (PhD student)<br /><br /><br /><br />Rui Costa (Undergraduate student)<br /><br /><a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://photos1.blogger.com/blogger/7093/2394/1600/teresa.jpg"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 76px; height: 96px;" src="http://photos1.blogger.com/blogger/7093/2394/400/teresa.jpg" alt="" border="0" /></a><br /><br /><a href="http://teresacunhaoliveira.blogspot.com/">Teresa Cunha Oliveira</a> (MSc, PhD)<div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/25601567-114441996519737339?l=mitochondrialdysfunction.blogspot.com' alt='' /></div>Teresa Cunha Oliveirahttp://www.blogger.com/profile/15891386575611824823noreply@blogger.com0